First, are the covariance adjusted averages among the four groups equal? (1)
Статья рассматривает статистические подходы к анализу данных ПЦР в реальном времени.
Подскажите пожалуйста, как правильно перевести предложение (1) в данном контексте:
Analysis of Covariance for Data Analysis
Another way to approach the real-time PCR data analysis is by using an analysis of covariance (ANCOVA), having the following model:
Ct = β0 + βconXicon + βgroupXigroup + βgroupconXigroupXicon +ε.
We are interested in two questions here. First, are the covariance adjusted averages among the four groups equal? Second, what is the Ct difference of target gene value between treatment and control sample after corrected by reference gene? In this case, the null hypothesis will be (µtargetgene_treatmentsample-µrefgene_treatmentsample)-(µ targetgene_controlsample -µ refgene_controlsample) = 0, and the test will yield a parameter estimation of ∆∆Ct.
Заранее благодарю.


