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This extends the total number of codon assignments for mammalian mRNA to 59, all assignments being identical to those for bacterial mRNA.
Контекст:
The R-dependent hydrolysis of ribosomal-bound fMettRNA
is directed by UAAA, UGAA, and UAGA, suggesting
that UAA, UGA, and UAG are chain termination codons for
mammalian cells. This extends the total number of codon
assignments for mammalian mRNA to 59, all assignments
being identical to those for bacterial mRNA. On the basis of
this universality, it appears probable that no other terminator
codons occur for the mammalian cell. The number of molecules
involved in the recognition of UAAA, UGAA, and UAGA
cannot be resolved from these studies.


